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Anti-GFRAL

Product Specifications

Synonyms

NGM120

Additionnal Information

Anti-GFRAL (NGM120) is a long-acting monoclonal antibody directed against glial-cell-derived neurotrophic factor (GDNF) family receptor alpha-like (GFRAL), with potential anti-anorexia and anti-cachexia activities. It binds to and blocks GFRAL activity which prevents binding of growth differentiation factor 15 (GDF15; MIC-1) to its receptor GFRAL and prevents GDF15/GFRAL-mediated signaling. MW: 145.5 KD.

Storage Conditions

Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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