Elezanumab (Anti-RGMA)
Product Specifications
CAS Number
1791416-49-3
Synonyms
ABT-555, AE12-1Y-QL
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Additionnal Information
Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa) . Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.
Storage Conditions
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.
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