Denosumab (anti-RANK ligand)
Product Specifications
CAS Number
615258-40-7
Synonyms
AMG-162
Target
NF-κB
Applications
NF-κB
Additionnal Information
Denosumab (anti-RANK ligand) (AMG-162) is a fully human monoclonal antibody that selectively inhibits primate RANKL. Denosumab inhibits the ability of human RANKL (143–317) to stimulate the formation of osteoclasts derived from murine RAW 264.7 cells with an IC50 value of 1.64 nM.
Storage Conditions
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
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