JYL 1421
JYL 1421 is a TRPV1 receptor antagonist, with an IC50 of 8 nM.
Product Specifications
CAS Number
401907-26-4
Product Name Alternative
SC 0030
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/JYL_1421.html
Purity
99.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CS(=O)(NC1=CC=C(CNC(NCC2=CC=C(C(C)(C)C)C=C2)=S)C=C1F)=O
Molecular Formula
C20H26FN3O2S2
Molecular Weight
423.57
References & Citations
[1]Jakab B, et al. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur J Pharmacol. 2005 Jul 4;517 (1-2) :35-44.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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