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JYL 1421

JYL 1421 is a TRPV1 receptor antagonist, with an IC50 of 8 nM.

Product Specifications

CAS Number

401907-26-4

Product Name Alternative

SC 0030

UNSPSC

12352005

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/JYL_1421.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CS(=O)(NC1=CC=C(CNC(NCC2=CC=C(C(C)(C)C)C=C2)=S)C=C1F)=O

Molecular Formula

C20H26FN3O2S2

Molecular Weight

423.57

References & Citations

[1]Jakab B, et al. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur J Pharmacol. 2005 Jul 4;517 (1-2) :35-44.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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