Thrombin (MW 37kDa)
Thrombin (MW 37kDa) is a Na+-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.
Product Specifications
CAS Number
[9002-04-4]
Product Name Alternative
ICI-118559
UNSPSC
12352005
Hazard Statement
H315, H317, H319, H334, H335
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Thrombin.html
Solubility
H2O
Smiles
[Thrombin(MW37kDa)]
Molecular Weight
37000 (Average)
Precautions
H315, H317, H319, H334, H335
References & Citations
[1]Golderman V, et al. Thrombin and the Protease-Activated Receptor-1 in Organophosphate-Induced Status Epilepticus. J Mol Neurosci. 2018 Dec 4.|[2]Krenzlin H, et al. The Importance of Thrombin in Cerebral Injury and Disease. Int J Mol Sci. 2016 Jan 11;17 (1) .|[3]Geetha T, et al. p62 serves as a shuttling factor for TrkA interaction with the proteasome. Biochem Biophys Res Commun. 2008 Sep 12;374 (1) :33-7.
Shipping Conditions
Room Temperature
Storage Conditions
Store at 4°C for 2 years, protect from light
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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