Thrombin (MW 37kDa)

Thrombin (MW 37kDa) is a Na+-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.

Product Specifications

CAS Number

[9002-04-4]

Product Name Alternative

ICI-118559

UNSPSC

12352005

Hazard Statement

H315, H317, H319, H334, H335

Target

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Thrombin.html

Solubility

H2O

Smiles

[Thrombin(MW37kDa)]

Molecular Weight

37000 (Average)

Precautions

H315, H317, H319, H334, H335

References & Citations

[1]Golderman V, et al. Thrombin and the Protease-Activated Receptor-1 in Organophosphate-Induced Status Epilepticus. J Mol Neurosci. 2018 Dec 4.|[2]Krenzlin H, et al. The Importance of Thrombin in Cerebral Injury and Disease. Int J Mol Sci. 2016 Jan 11;17 (1) .|[3]Geetha T, et al. p62 serves as a shuttling factor for TrkA interaction with the proteasome. Biochem Biophys Res Commun. 2008 Sep 12;374 (1) :33-7.