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Nitroxoline (Standard)

Nitroxoline (Standard) is the analytical standard of Nitroxoline. This product is intended for research and analytical applications. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research[1][2][3].

Product Specifications

CAS Number

4008-48-4

Product Name Alternative

8-Hydroxy-5-nitroquinoline (Standard) ; 5-Nitro-8-quinolinol (Standard)

UNSPSC

12352005

Target

Antibiotic; Apoptosis; Autophagy; Bacterial; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Autophagy; Others

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/nitroxoline-standard.html

Smiles

OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1

Molecular Formula

C9H6N2O3

Molecular Weight

190.16

References & Citations

[1]Jin-Guo Yu, et al. Nitroxoline induces cell apoptosis by inducing MDM2 degradation in small-cell lung cancer. Kaohsiung J Med Sci. 2019 Apr;35 (4) :202-208. |[2]A Sobke, et al. The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Antimicrob Agents Chemother. 2012 Nov;56 (11) :6021-5.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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