Cytochalasin C

Cytochalasin C is a cell-permeable fungal toxin and induces the formation of nuclear rodlets. Cytochalasin C is 10 times less toxic in mice than is cytochalasin D[1][2][3].

Product Specifications

CAS Number

[22144-76-9]

UNSPSC

12352005

Hazard Statement

H300+H310+H330, H361

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cytochalasin-c.html

Purity

99.85

Solubility

10 mM in DMSO

Smiles

CC1=C(C)[C@@H](O)[C@@](/C=C/C[C@@H]2C)([H])[C@](C(N[C@H]3CC4=CC=CC=C4)=O)([C@]31[H])[C@H](OC(C)=O)/C=C/[C@](O)(C)C2=O

Molecular Formula

C30H37NO6

Molecular Weight

507.62

Precautions

H300+H310+H330, H361

References & Citations

[1]Foissner I, et al. Wide-ranging effects of eight cytochalasins and latrunculin A and B on intracellular motility and actin filament reorganization in characean internodal cells. Plant Cell Physiol. 2007 Apr;48 (4) :585-97.|[2]Yahara I, et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular eventsand those on actin in vitro. J Cell Biol. 1982 Jan;92 (1) :69-78.|[3]Trendowski M, et al. Tolerated doses in zebrafish of cytochalasins and jasplakinolide for comparison with tolerateddoses in mice in the evaluation of pre-clinical activity of microfilament-directed agents in tumormodel systems in vivo. In Vivo. 2014 Nov-Dec;28 (6) :1021-31.