MT 63-78
Product Specifications
UNSPSC Description
MT 63-78 is a specific and potent direct AMPK activator with an EC50 of 25 μM. MT 63–78 also induces cell mitotic arrest and apoptosis. MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects[1].
Target Antigen
AMPK; Apoptosis; mTOR
Type
Reference compound
Related Pathways
Apoptosis;Epigenetics;PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mt-63-78.html
Purity
98.50
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
N#CC1=CNC2=C1C=C(C3=CC=C(C4=C(O)C=CC=C4O)C=C3)C=C2
Molecular Weight
326.35
References & Citations
[1]Zadra G, et al. A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis. EMBO Mol Med. 2014 Apr;6(4):519-38.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W058849/MT-63-78-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W058849/MT-63-78-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1179347-65-9
Available Sizes
Curated Selection
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