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Sp-6-Phe-cAMPS

Sp-6-Phe-cAMPS is a potent, site-selective and membrane-permeable activator of cAMP-dependent protein kinase. Sp-6-Phe-cAMPS does not activate exchange factors directly activated by cAMP and can therefore be used as an Epac negative control. Sp-6-Phe-cAMPS can be used in the study of neurodegenerative diseases[1].

Product Specifications

CAS Number

[169335-92-6]

UNSPSC

12352005

Target

PKA

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sp-6-phe-camps.html

Smiles

O[C@@H]1[C@H](O2)[C@@H](CO[P@]2(S[Na])=O)O[C@H]1N(C=N3)C4=C3C(NC5=CC=CC=C5)=NC=N4

Molecular Formula

C16H15N5NaO5PS

Molecular Weight

443.35

References & Citations

[1]Naz, et al. Repercussion of cAMP and EPAC in Memory and Signaling. Drug Research (2022) : 65-71.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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