TRUPCR® NPM1 Qualitative KIT
• CE–IVD • TRUPCR® NPM1 Qualitative Kit allows initial diagnosis and stratifying high and low risk AML. • Reliable and sensitive detection of NPM1 A, B and D mutations. • The kit offers sensitivity to detect up to 1% mutant allele in background of 99% wild type allele. • It is compatible with various Real Time PCR instruments. • Easy-to-use, rapid, reliable, comprehensive and cost-effective tests.
Product Specifications
Applications Notes
The Nucleophosmin (NPM1) gene is one of the most commonly mutated genes in acute myeloid leukemia (AML), occurring in about 35% of AML patients at diagnosis and in approximately 60% of adult cytogenetically normal AML (CN-AML) . TRUPCR® NPM1 Qualitative Kit is an in-vitro nucleic acid amplification assay for the qualitative detection of mutation in NPM1 gene in peripheral blood samples.The detection is achieved using fluorescent probes. TRUPCR® NPM1 Qualitative Kit is a two tube assay composed of primer probe mixture for the detection of the NPM1 mutation and a reference control gene.Three types of NPM1 mutation variants detected by this kit are given below:
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