TRUPCR® NPM1 Qualitative KIT

The Nucleophosmin (NPM1) gene is one of the most commonly mutated genes in acute myeloid leukemia (AML), occurring in about 35% of AML patients at diagnosis and in approximately 60% of adult cytogenetically normal AML (CN-AML) . TRUPCR® NPM1 Qualitative Kit is an in-vitro nucleic acid amplification assay for the qualitative detection of mutation in NPM1 gene in peripheral blood samples.The detection is achieved using fluorescent probes. TRUPCR® NPM1 Qualitative Kit is a two tube assay composed of primer probe mixture for the detection of the NPM1 mutation and a reference control gene.Three types of NPM1 mutation variants detected by this kit are given below: