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Boc-Gln-Arg-Arg-AMC (acetate)

Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC) . AMC is fluorescent under UV light and can emit a fluorescent signal[1].

Product Specifications

CAS Number

2223665-74-3

UNSPSC

12352209

Target

Fluorescent Dye

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/boc-gln-arg-arg-amc-acetate.html

Purity

99.25

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(O)=O.CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O

Molecular Formula

C34H53N11O10

Molecular Weight

775.85

References & Citations

[1]Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35 (14) :1832-46.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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