Urocortin, Human
Peptide to Urocortin, Human
Product Specifications
CAS Number
176591-49-4
Structure Composition
Ac-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
Applications
Using a genomic library, human urocortin (UCN) has been cloned and localized to human chromosome 2. Human and rat urocortin share 95% identity within the mature peptide region. Human urocortin binds with high affinity to CRF receptor types 1, 2α, and 2β, stimulates cAMP accumulation from cells transfected with these receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells.
Purity
> 95%
Form
Lyophilized powder, acetate salt before lyophilization
Molecular Formula
C204H337N63O64
Molecular Weight
4737.3
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic
Available Sizes
Curated Selection
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