[D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P
Peptide to [D-Arg1, D-Trp5, 7, 9, Leu11]-Substance P
Product Specifications
CAS Number
122481-75-8
Structure Composition
D-Arg-Pro-Lys-Pro-D-Trp-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2
Applications
This substance P analog is a very potent broad-spectrum neuropeptide inhibitor for small cell lung cancer (SCLC) cell growth in vitro (IC50 = 5 μM) . Moreover it potently inhibited signal transduction pathways in vitro and significantly delayed the growth of an SCLC xenograft in vivo. It could therefore be of therapeutic value in SCLC.
Purity
> 95%
Form
Lyophilized powder
Molecular Formula
C81H110N20O12
Molecular Weight
1555.91
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic
Available Sizes
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