[Pyr1]-Apelin-13
Peptide to [Pyr1]-Apelin-13
Product Specifications
CAS Number
217082-60-5
Structure Composition
Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
Applications
The pyroglutamyl form of apelin-13 exhibited a high activity with an EC50 value of 0.30 nM. pERPRLSHKGPMPF is probably the final product of the post-translational modification of apelin and the biologically active endogenous ligand. [Pyr1]-Apelin-13 has been identified as the predominant apelin isoform in the human heart. Pyr-Apelin-13 stimulates glucose utilization in normal and obese insulin-resistant mice. It could be required for the maintenance of insulin sensitivity.
Purity
> 95%
Form
Lyophilized powder
Molecular Formula
C69H108N22O16S
Molecular Weight
1533.85
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic
Available Sizes
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