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Urocortin, Human

Peptide to Urocortin, Human

Product Specifications

CAS Number

176591-49-4

Structure Composition

H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2

Applications

Using a genomic library, human urocortin (UCN) has been cloned and localized to human chromosome 2. Human and rat urocortin share 95% identity within the mature peptide region. Human urocortin binds with high affinity to CRF receptor types 1, 2α, and 2β, stimulates cAMP accumulation from cells transfected with these receptors and acts in vitro to release ACTH from dispersed rat anterior pituitary cells.

Purity

> 95%

Form

Lyophilized powder

Molecular Formula

C204H337N63O64

Molecular Weight

4696.3

Storage Conditions

Shipped at 4°C. Store at -20°C for one year.

Light Source

Synthetic

Available Sizes

Curated Selection

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