GLP-2, Rat
Peptide to GLP-2, Rat
Product Specifications
CAS Number
195262-56-7
Structure Composition
H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Thr-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH
Product Name Alternative
Glucagon-Like Peptide 2 (rat), Preproglucagon (146-178) (rat), Proglucagon (126-158) (rat)
Applications
GLP-2 administration to mice or rats promotes stimulation of crypt cell proliferation and inhibition of enterocyte apoptosis resulting in hyperplasia of the small bowel villous epithelium. It also exerts trophic effects in animal models of both small and large bowel injury such as experimental small bowel resection or chemically induced colitis. In addition to stimulation of epithelial proliferation, GLP-2 also acutely regulates gastric emptying and exerts rapid metabolic effects promoting stimulation of intestinal hexose transport. The actions of GLP-2 are transduced via the GLP-2 receptor, a member of the glucagon-secretin G protein-coupled receptor superfamily.
Purity
> 95%
Form
Lyophilized powder
Molecular Formula
C166H256N44O56S
Molecular Weight
3796.22
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic
Available Sizes
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