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Mmu-miR-449b miRNA Agomir

Synthetic miRNA Agomir is used to regulate the expression of target mmu-miR-449b mRNA.

Product Specifications

Reactivity

M

Source

Synthetic

Form

Lyophilized powder

Components

This synthetic miRNA is based on the mature miRNA sequence. The antisense strand of the agomir has 2 phosphorothioates at the 5' end, 4 phosphorothioates, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. It exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Storage Conditions

Shipped at 4 °C. Store at -20 °C for one year. Avoid freeze-thaw cycles after reconstitution.

Specificity

Agomir is chemically-modified double-strand miRNA mimics which can mimic mature endogenous miRNAs after transfection into cells. They can up-regulate the endogenous miRNA activity by utilizing the natural miRNA machinery. Our miRNA agomir is designed to mimic mature miRNAs, and chemically modified to increase their stability and activity.

NCBI Gene Symbol

Mmu-miR-449b

Accession Number Mouse

MIMAT0005447

Available Sizes

Frequently Asked Questions

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