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Recombinant Dog Erythropoietin receptor (EPOR), partial

Product Specifications

Product Name Alternative

EPO-R

Abbreviation

Recombinant Dog EPOR protein, partial

Gene Name

EPOR

UniProt

Q2KL21

Expression Region

25-250aa

Organism

Canis lupus familiaris (Dog) (Canis familiaris)

Target Sequence

ASLPKPLDPKFESKAALLAARAPEELLCFTERLEDLVCFWEEAASAGVGPDNYSFFYQLEGEPWKTCSLHQAPTTRGAVRFWCSLPTADTSSFVPLELRATAVSSGALLYRRIIHINEVVLLDPPAGLLARRADEGGHVVLRWLPPPGAPVASLIRYEVNISGSVAGGSQKVEILDGRTECVLSNLRGGTRYTFMVRARMAEPSFGGFWSAWSEPASLLTASDLDP

Tag

C-terminal 6xHis-tagged

Type

In Stock Protein

Source

E.coli

Field of Research

Cardiovascular

Relevance

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate LYN tyrosine kinase

Endotoxin

Not test

Purity

Greater than 85% as determined by SDS-PAGE.

Activity

Not Test

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Molecular Weight

25.5 kDa

References & Citations

"Transcriptional regulation of EPO-R during lung growth." Zhang Q., Moe O.W., Hsia C.C.W. Submitted (JAN-2005)

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Protein Length

Partial

Available Sizes

Frequently Asked Questions

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