(S, R, S) -AHPC-Me-12- ((4-Bromobutyl) amino) dodecanamide
Selected Variant
HY-168290
Size: 1 Each
(S, R, S) -AHPC-Me-12- ((4-Bromobutyl) amino) dodecanamide incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S, R, S) -AHPC-Me-12- ((4-Bromobutyl) amino) dodecanamide can be used in the synthesis of PROTACs, such as MS934. MS934 is a novel improved VHL-recruiting MEK 1/2 PROTAC degrader[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-me-12-4-bromobutyl-amino-dodecanamide.html
Smiles
CC(C)(C)[C@H](NC(CCCCCCCCCCCNCCCCBr)=O)C(N1[C@@H](C[C@H](C1)O)C(N[C@H](C2=CC=C(C3=C(N=CS3)C)C=C2)C)=O)=O
Molecular Formula
C39H62BrN5O4S
Molecular Weight
776.91
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Frequently Asked Questions
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