Imgatuzumab

Imgatuzumab (RG 7160) is a humanized monoclonal antibody against the EGFR. Imgatuzumab acts as an immunomodulator. Imgatuzumab can be used in research of cancer[1].

Product Specifications

CAS Number

[959963-46-3]

Product Name Alternative

RG 7160; RO 5083945; Anti-EGFR Recombinant Antibody

UNSPSC

12352203

Target

EGFR

Type

Inhibitory Antibodies

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/imgatuzumab.html

Purity

99.41

Solubility

10 mM in DMSO

Smiles

[Imgatuzumab]

Molecular Weight

(145.28 kDa)

References & Citations

[1]Gonzalez-Nicolini V, et, al. Premedication and Chemotherapy Agents do not Impair Imgatuzumab (GA201) -Mediated Antibody-Dependent Cellular Cytotoxicity and Combination Therapies Enhance Efficacy. Clin Cancer Res. 2016 May 15;22 (10) :2453-61.