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CRTh2 antagonist 2

CRTh2 antagonist 2 is selective and potent CRTH2 antagonist extracted from patent US20140148470A1, compound Example 1, has an IC50 of ≤10 nM. CRTh2 antagonist 2 can be used in research of androgenic alopecia[1].

Product Specifications

CAS Number

780763-95-3

UNSPSC

12352005

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/crth2-antagonist-2.html

Purity

99.78

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(O)CC1=C(N(C)C)N=C(CC2=CC=C(NC(C3=CC=C4C=CC=CC4=C3)=O)C=C2)N=C1Cl

Molecular Formula

C26H23ClN4O3

Molecular Weight

474.94

References & Citations

[1]Andreas Schnapp, et al. Pyrimidine compounds for treating hairloss. US20140148470A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DP

Frequently Asked Questions

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