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FaX-IN-1

FaX-IN-1 (compound 11A) is an intermediate in the preparation of FaX inhibitors and was used to study the inhibitory activity against venous thrombosis in rats[1].

Product Specifications

CAS Number

503614-91-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Factor Xa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/fax-in-1.html

Purity

99.91

Solubility

10 mM in DMSO

Smiles

O=C(N(C(C=C1)=CC=C1N(CCCC2)C2=O)CC3)C4=C3C(C(OCC)=O)=NN4C5=CC=C(OC)C=C5

Molecular Formula

C27H28N4O5

Molecular Weight

488.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Wang Y, Sun X, Yang D, Guo Z, Fan X, Nie M, Zhang F, Liu Y, Li Y, Wang Y, Gong P, Liu Y. Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element. Bioorg Med Chem. 2016 Nov 1;24 (21) :5646-5661.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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