Kulactone
Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB) [1][2].
Product Specifications
CAS Number
22611-36-5
UNSPSC
12352005
Target
Bacterial; Fungal; Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kulactone.html
Purity
98.25
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]12[C@]([C@@]3([H])[C@](OC([C@@H]3CC/C=C(C)/C)=O)([H])C1)(CC[C@@]4([H])C2=CC[C@]5([H])[C@@]4(CCC(C5(C)C)=O)C)C
Molecular Formula
C30H44O3
Molecular Weight
452.67
References & Citations
[1]Rahab W Kamau, et al. Antimicrobial compounds from root, stem bark and seeds of Melia volkensii. Nat Prod Res. 2016 Sep;30 (17) :1984-7.|[2]Vivek Dhar Dwivedi, et al. Mechanistic insights into the Japanese Encephalitis Virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica. bioRxiv, 2021.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Plasmodium
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