Kulactone

Kulactone, a natural bioflavonoid and an inhibitor against jRdRp, possesses antifungal, antibacterial and antiplasmodial activities. Kulactone exhibit no crossing through Blood Brain Barrier (BBB) [1][2].

Product Specifications

CAS Number

[22611-36-5]

UNSPSC

12352005

Target

Bacterial; Fungal; Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/kulactone.html

Purity

98.25

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@@]12[C@]([C@@]3([H])[C@](OC([C@@H]3CC/C=C(C)/C)=O)([H])C1)(CC[C@@]4([H])C2=CC[C@]5([H])[C@@]4(CCC(C5(C)C)=O)C)C

Molecular Formula

C30H44O3

Molecular Weight

452.67

References & Citations

[1]Rahab W Kamau, et al. Antimicrobial compounds from root, stem bark and seeds of Melia volkensii. Nat Prod Res. 2016 Sep;30 (17) :1984-7.|[2]Vivek Dhar Dwivedi, et al. Mechanistic insights into the Japanese Encephalitis Virus RNA dependent RNA polymerase protein inhibition by bioflavonoids from Azadirachta indica. bioRxiv, 2021.