PD-L1 ligand 1
PD-L1 ligand 1 is a PROTAC target protein ligand. PD-L1 ligand 1 can be used as a PD-L1 degrader[1].
Product Specifications
UNSPSC
12352101
Target
Ligands for Target Protein for PROTAC; PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pd-l1-ligand-1.html
Smiles
ClC1=C(C=CC=C1C2=CC=CC=C2F)COC3=CC(OCC4=CC(C#N)=CN=C4)=C(C=C3)CO
Molecular Formula
C27H20ClFN2O3
Molecular Weight
474.91
References & Citations
[1]Zhang F, et al. Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction. Bioorg Med Chem. 2024 Sep 1;111:117867.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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