Recombinant COVID-19 S-trimer Protein (Omicron, B.1.1.529)
Recombinant COVID-19 S-trimer Protein (Omicron, B.1.1.529) is produced by our mammalian expression system and the target gene encoding Cys15-Gln1208 is expressed with a 6His tag at the C-terminus. A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, N764K, D796Y, N856K, Q954H, N969K and L981F mutations were identified in the COVID-19 variant (known as Omicron/B.1.1.529 lineage) which emerged in South Africa. Two proline substitutions and furin cleavage site substitutions are introduced to stabilize the trimeric prefusion state of COVID-19 S protein and abolish the furin cleavage site, respectively.
Product Specifications
Product Name Alternative
SARS-CoV-2 RBD Protein; SARS-CoV-2 Spike RBD Protein; SARS-CoV-2 S Protein RBD
Reactivity
COVID-19
Source
Human cells
Applications
E, WB, SDS-PAGE, MS
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Form
Liquid in a 0.2 μm filtered solution of PBS, pH 7.4.
Storage Conditions
Store it at -20°C to -80°C for one year. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Quality Control
Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
SwissProt (Human)
P0DTC2
Entrez GeneHuman
43740568
Available Sizes
Frequently Asked Questions
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