Recombinant Human TNF Protein
Recombinant Human TNF Protein is produced by E. coli using rDNA technology. The protein consists of three identical polypeptide chains of 158 amino acids combined to form a compact bell-shaped homotrimer. The individual subunits have a relative molecular mass of 17484 Daltons each. TNF-α is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
Product Specifications
Structure Composition
Product Name Alternative
TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a
Reactivity
H
Source
E. coli
Applications
E, WB, SDS-PAGE, MS
Purity
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Form
Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Storage Conditions
NCBI Gene Symbol
TNF
Quality Control
Endotoxin: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
SwissProt (Human)
P01375
Entrez GeneHuman
7124
Available Sizes
Frequently Asked Questions
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