Wasabi Receptor Toxin (TFA)

Wasabi Receptor Toxin TFA (WaTx TFA) is the TFA salt form of Wasabi Receptor Toxin (HY-P5914) . Wasabi Receptor Toxin TFA is a cell-penetrating scorpion toxin. Wasabi Receptor Toxin TFA is the activator for TRPA1 ion channel with EC50 in nanomolar level, and prolongs the channel open time, but reduces Ca2+ permeability. Wasabi Receptor Toxin TFA causes thermal hypersensitivity and mechanical allodynia in rats, without triggering neurogenic inflammation[1].

Product Specifications

Product Name Alternative

WaTx (TFA)

UNSPSC

12352209

Target

TRP Channel

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/wasabi-receptor-toxin-tfa.html

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H](N)C)N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H]3CCC(N)=O)=O)CC(O)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)C(C)C)=O)CCCCN)=O)CC(N)=O)=O)C(C)C)=O)CC(N)=O)=O)CSSCC(NC3=O)C(N[C@H](C(N[C@H](C(N[C@H]5CCSC)=O)CCC(N)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CCC(N)=O)=O)CCC(O)=O)=O)CC7=CC=C(O)C=C7)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N8[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CC(C)C)=O)CCC8)=O)CO)=O)=O)CC9=CC=C(O)C=C9)=O)CCCCN)=O)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)CCC1)=O)CO.OC(C(F)(F)F)=O.[x]