DBCO-PEG4-C2-acid
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-PEG4-C2-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
1537170-85-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-peg4-c2-acid.html
Purity
99.22
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
O=C(O)CCOCCOCCOCCOCCNC(CCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O
Molecular Formula
C30H36N2O8
Molecular Weight
552.62
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GM-47-5 1 mL
Colloidal Gold Conjugated Monoclonal Antibody to Hepatitis B Surface Antigen, 5nm
Sign In for Pricing
View Details 
BNC880104-500 1x 500 µL
Eosinophil Peroxidase (EPO104), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 