LBM-415
LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy[1].
Product Specifications
CAS Number
478913-91-6
Product Name Alternative
NVP-PDF 713; VIC-104959
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lbm-415.html
Smiles
O=C([C@H]1N(C([C@@H](CN(C=O)O)CCCC)=O)CCC1)NC2=CC=C(F)C=[N+]2[O-]
Molecular Formula
C18H25FN4O5
Molecular Weight
396.41
References & Citations
[1]Fritsche TR, et al. Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance. Antimicrob Agents Chemother. 2005 Apr;49 (4) :1468-76.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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