α-Latrotoxin

Product Specifications

CAS Number

65988-34-3

Certification

RUO

UniProt

P23631

Source

Isolated from Latrodectus tredecimguttatus .

Purification

Migrates as one distinct band when run on a 5-25% gradient polyacrylamide gel according to the method of Laemmli (Nature 227, 680 (1970) ) .

Stability

As indicated on product label or CoA when stored as recommended. Stock solution is stable for 1 week when stored at +4°C or for at least one year at -20°C.

Purity

≥97%

Reconstitution

Reconstitute in 0.5ml of distilled cold water. Stir very gently. Do not shake or vortex. Add 0.5 ml glycerol. Stock solution received contains 50% glycerol and 300nM α-latrotoxin.

Molecular Weight

~130kDa.

Shipping Conditions

Ambient Temperature

Storage Conditions

-20°C

Notes

Attention: For best results, only proceed according to the given instructions. Dissolution and/or storage of this toxin contrary to these instructions may affect the stability and biological activity of this compound.

Formulation

Lyophilized.

Quality Control

Bioassay: Test of the ability to stimulate neurotransmitter release in both Ca 2+ -free and Ca 2+ -containing media according to Valtorta. Effective concentration: 100pM-1nM.