UDP-GalNAz

Transfer of GalNAz moiety to GalNAc residues of proteins and monoclonal antibodies with β-1,4-galactosyltranferase mutant Y289L-Gal-T1. The azide-functionalized target can subsequently be detected via Cu (I) -catalyzed or Cu (I) -free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or a fluorophore (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.