Spermine NONOate
Product Specifications
CAS Number
136587-13-8
Product Name Alternative
SPER/NO, (Z) -1-{N-[3-Aminopropyl]-N-[4- (3-aminopropylammonio) butyl]-amino}-diazen-1-ium-1,2-diolate
Certification
RUO
Stability
As indicated on product label or CoA when stored as recommended. Relatively stable in alkaline solution.
Purity
≥97% (NMR)
Solubility
Soluble in water, methanol or 100% ethanol.
Molecular Formula
C 10 H 26 N 6 O 2
Molecular Weight
262.4
Shipping Conditions
Blue Ice
Storage Conditions
-80°C
Notes
Product dissociates to the free amine and nitric oxide in a pH dependent manner following first order kinetics. Alkaline solutions of NONOates (in 0.01M NaOH) are stable and can be stored at 0°C for 24 hours. To initiate the release of nitric oxide add alkaline solution of Spermine NONOate to excess buffer of pH 7.0 – 7.4. Relatively high concentrated solutions can be prepared for further dilution. Half life in 0.1M phosphate buffer (pH 7.4) at 37 C is t1⁄2 (min.) 39. Decomposition is nearly instantaneous at pH 5.
Appearance
White to off-white crystalline solid.
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