What is the catalog number for MMP-14 (catalytic domain) (human), (recombinant)?

The catalog number for MMP-14 (catalytic domain) (human), (recombinant) is BML-SE259-0010.

What sizes are available for MMP-14 (catalytic domain) (human), (recombinant)?

MMP-14 (catalytic domain) (human), (recombinant) is available in the following size(s): 10 µg.

Is MMP-14 (catalytic domain) (human), (recombinant) in stock?

MMP-14 (catalytic domain) (human), (recombinant) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for MMP-14 (catalytic domain) (human), (recombinant)?

MMP-14 (catalytic domain) (human), (recombinant) is requires dry ice shipping.

MMP-14 (catalytic domain) (human), (recombinant)

Product Specifications

Specifications

≥1000 pmol/min/μg at 37°C using the colorimetric thiopeptolide Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt (100 μM; Prod. No. BML-P125) as substrate.

Product Name Alternative

Matrix metalloproteinase 14, Membrane type matrix metalloproteinase 1, MT-1 MMP

Certification

RUO

UniProt

P50281

Source

Produced in E.coli . Active Matrix Metalloproteinase-14 (MMP-14, Membrane-Type Matrix Metalloproteinase 1, MT1-MMP) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-14 (Tyr 112 -Arg 298 , NM_004995) with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-14 which lacks the C-terminal hemopexin domain. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected.

Purification

Partially purified by single-step affinity chromatography and gel filtration.

Stability

The enzyme is stable on ice for at least several hours. However, it is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay. NOTE: When stored at -70°C, this enzyme is stable at the concentration supplied, in its current storage buffer. Procedures such as dilution of the enzyme followed by refreezing could lead to loss of activity.