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Matrix metalloproteinase-3 (MMP-3) fluorometric drug discovery kit, GREEN

Selected Variant

BML-AK303-0001

Size: 96 Well

Product Specifications

Product Name Alternative

Stromelysin-1, Transin-1

Certification

RUO

UniProt

P08254

Applications

Activity assay, Fluorescent detection, HTS

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Notes

NCBI Reference Sequence: NM_002422 The MMP-3 Fluorogenic Substrate offers key advantages over other MMP substrates. Emission at the green end of the spectrum avoids the interference at lower wavelengths often exhibited by screening compounds, and by substances commonly found in biological samples and tissue culture medium. The ultra-strong fluorescence of this substrate allow for substrate concentrations much lower than the K m , a condition generally desirable in inhibitor screening/kinetics assays.

Applications Notes

Designed to screen MMP-3 inhibitors using a quenched fluorogenic substrate.

Contents

1 vial MMP-3 enzyme 1 vial substrate (MMP-3 fluorogenic substrate) 1 vial 5-FAM calibration standard 1 vial control inhibitor (NNGH) 1 bottle (20 ml) assay buffer 1 black 96-well microplate Instructions

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