LSD1 (human), (recombinant)
Product Specifications
Specifications
≥20 U/μg. One U=1 pmol/min at 30°C, 100 μM Histone H3 Dimethyl Lysine-4 Peptide (Prod. No. BML-P256) .
Product Name Alternative
KDM1, Lysine-specific histone demethylase 1, BHC110, AOF2, KIAA0601
Certification
RUO
UniProt
O60341
Source
Produced in E. coli .
Sequence
N-terminal truncation of LSD1 from human cDNA. Sequence is identical to Genbank accession NM015013 (aa 151-852) .
Purification
Purified by multi-step chromatography.
Stability
The enzyme is stable on ice for the time typically required to set up an experiment (30-60 min.), but may lose activity with prolonged storage on ice. It is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay. The remaining, unused, undiluted enzyme should be refrozen quickly by, for example, snap freezing in a dry/ice ethanol bath or liquid nitrogen. Freezing and storage of diluted enzyme is not recommended.
Purity
≥90% (SDS-PAGE)
Molecular Weight
78 kDa
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Formulation
Liquid. In 8.1mM Na 2 HPO 4 , 1.5mM KH 2 PO 4 , pH 7.2, 138mM sodium chloride, 2.7mM KCl and 40% v/v glycerol.
Applications Notes
Useful tool to study LSD1 kinetics and inhibitor sensitivity and also the effect of the enzyme in transcriptional regulation, cell cycle progression, and oncogenesis.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042125-100 1x 100 µL
Ksp-Cadherin / CDH16 (Renal Cell Marker) (CDH16/2125), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
GP-1301-15 1 mL
Colloidal Gold Conjugated Glycine max Lectin (Soybean) -SBA-, 15nm
Sign In for Pricing
View Details 