LAG-3 (human) :Fc (human), (recombinant)

Lymphocyte activation gene-3, FDC protein, CD223

RUO

P18627

Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1.

Stable for at least 6 months after receipt when stored at -20°C.

<0.1EU/mg purified protein (LAL test; Bio Whittaker) .

≥99% (SDS-PAGE)

Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.

~80kDa (SDS-PAGE) .

Blue Ice

-20°C

Binds to human, mouse and monkey MHC class II.

Liquid. In PBS.

Flow Cytometry: Detection of MHC class II molecules in combination with fluorescently labelled Ab to IgG1.