HIGHDEF®blue IHC chromogen (AP)

The HIGHDEF ® blue IHC chromogen (AP) is a substrate-chromogen system designed to be used for either IHC or ISH when utilizing alkaline phosphatase. It has been formulated for increased stability of the working solution while producing a distinct bright blue color. It is insoluble in alcohol and xylene substitutes (both aliphatic hydrocarbon and citrus based) ; therefore sections can be dehydrated in alcohol, cleared in xylene substitute, and permanently mounted. However, we recommend air drying slides and then permanently mounting. This chromogen substrate system may be used for both automation and manual use.