Fibroblast activation protein (human) monoclonal antibody (F11-24)

Immunohistochemistry (suitable for stainings on unfixed, acetone-fixed or ethanol-fixed frozen sections; acetone-fixed frozen sections showed optimal staining results) Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.

FAP is a cell surface glycoprotein of reactive human fibroblasts. Among the normal adult organs tested, MAb to FAP does not show immunoreactivity in immunohistological studies with either resting fibroblasts (fibrocytes) of the normal organ mesenchyme or the parenchymal cells. The single exception noted is a subset of endocrine cells in the pancreatic islets, presumably glucagon-producing A cells.