FGFR/β-Klotho Reporter Assay System

The principal application of this reporter assay is in the screening of test materials to quantify any functional interactions, either activating or inhibitory, that they may exert against FGFR1c/β-Klotho or the coupled RAS-MAPK pathway.

This Human Fibroblast Growth Factor Receptor 1c and β-Klotho (FGFR/β-Klotho) assay kit is an all-inclusive assay system that includes addition to FGFR/β-Klotho Reporter Cells, an optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample treatments, the physiological endocrine activator FGF-21, Luciferase Detection Reagents, and a cell culture-ready assay plate.