DEA NONOate

Product Specifications

CAS Number

372965-00-9

Product Name Alternative

DEA/NO, 2- (N, N-Diethylamino) -diazenolate-2-oxide . diethylammonium salt

Certification

RUO

Stability

As indicated on product label or CoA when stored as recommended. Store, as supplied, at-80°C for up to 1 year. Aqueous solutions should be prepared fresh daily.

Purity

≥97% (NMR)

Solubility

Soluble in 100% ethanol (25mg/ml), DMSO (2mg/ml), dimethyl formamide (2mg/ml) or PBS, pH 7.2 (10mg/ml) .

Molecular Formula

C 4 H 10 N 3 O 2 . C 4 H 12 N

Molecular Weight

132.1 . 74.1

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Notes

Dissociates to the free amine and nitric oxide in a pH-dependent manner following first order kinetics. To initiate the release of nitric oxide, add stock alkaline solution of DEA NONOate to excess buffer of pH 7.0 – 7.4. The half life in 0.1 M phosphate buffer, pH 7.4, is t1⁄2 = 16 min. at 22 -25 °C or t1⁄2= 2 min. at 37 °C. Liberates 1.5 mol of NO per mol of parent compound. Decomposition is nearly instantaneous at pH 5.0.