CFTR monoclonal antibody (CF3)
Product Specifications
Product Name Alternative
Cystic fibrosis transmembrane conductance regulator, ABCC7
Certification
RUO
UniProt
P13569
Host
Mouse
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide corresponding to aa 103-117 (G103RIIASYDPDNKEER117) in the first extracellular loop of human and rabbit CFTR (cystic fibrosis transmembrane conductance regulator) . This sequence is highly conserved in mouse, sheep, bovine and Xenopus laevis CFTR.
Clone
CF3
Applications
ICC, IP, WB
Dilution
Immunocytochemistry (1:500; staining of CFTR in mouse epithelial cells results in cell surface staining, consistent with localization at the plasma membrane. Antibody also detects one or more immunologically related proteins in murine cell line Heb7a that does not contain CFTR mRNA.) Western Blot (1:500) Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Formulation
Liquid. Diluted ascites containing 0.05% sodium azide.
Applications Notes
Detects a band of ~170kDa by Western blot. Functional Application: inhibits epithelial uptake of S. typhi in some mouse cell lines.
Warranty
This antibody is covered by our Worry-Free Guarantee .
Isotype
IgM
Cross Reactivity Details
Cross-reacts with related proteins in mouse cell line Heb7a that doesn not contain CFTR mRNA.
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