CD18 (human) monoclonal antibody (MEM-48)
Product Specifications
Product Name Alternative
β2 integrin
Certification
RUO
UniProt
P05107
Host
Mouse
Species Reactivity
Human
Immunogen
Leukocytes from a patient suffering from a LGL-type leukemia.
Clone
MEM-48
Applications
Flow Cytometry, FUNC, IHC (FS), IP, WB
Purification
Protein A-affinity purified.
Dilution
Immunohistochemistry (paraffin sections: recommended dilution 10μg/ml, positive tissue: spleen, microglia; frozen sections) Western Blot (Recommended dilution: 2μg/ml in buffer containing laurylmaltoside, 2x non-reducing SDS; SDS-PAGE (6% separating gel, 4% stacking gel) positive control: Kg-1a human leukemia cell lysate) Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Specificity
Recognizes residues 534-546 in cysteine-rich repeat 3 of CD18 (β2 integrin) .
Formulation
Liquid. In PBS, pH 7.4, containing 15mM sodium azide.
Applications Notes
Functional Application: induces high-affinity LFA-1 conformation in leukocytes
Warranty
This antibody is covered by our Worry-Free Guarantee .
Isotype
IgG1
Cross Reactivity Details
Cross-reacts with all three leukocyte integrins.
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