BCMA (human) :Fc (human), (recombinant)
Product Specifications
Product Name Alternative
TNFRSF 17, B cell maturation protein, CD269
Certification
RUO
UniProt
Q02223
Source
Produced in HEK 293 cells. The extracellular domain of human BCMA (aa 2-54) is fused at the C-terminus to the Fc portion of human IgG1.
Stability
Stable for at least 6 months after receipt when stored at -20°C.
Concentration
1 mg/mL after reconstitution.
Purity
≥95% (SDS-PAGE)
Reconstitution
Reconstitute with 50μl of sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Molecular Weight
~40kDa (SDS-PAGE) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Notes
Historical data shows that it blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation.
Specificity
Binds human and mouse BAFF and APRIL.
Formulation
Lyophilized. Contains PBS.
Applications Notes
ELISA: binds to mouse BAFF) . Flow Cytometry: Detection of membrane-bound mouse BAFF and human APRIL in combination with fluorescently labelled Ab to IgG1.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog