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ITX5061

ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1) .

Product Specifications

CAS Number

1252679-52-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; HCV; p38 MAPK

Type

Reference compound

Related Pathways

Anti-infection; Autophagy; MAPK/ERK Pathway

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ITX5061.html

Purity

99.69

Solubility

DMSO : ≥ 83.3 mg/mL

Smiles

O=C(NC1=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C1OC)C(C2=C3C=CC=CC3=C(OCCN4CCOCC4)C=C2)=O.Cl

Molecular Formula

C30H38ClN3O7S

Molecular Weight

620.16

Precautions

H302, H315, H319, H335

References & Citations

[1]Masson D, et al. Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. Arterioscler Thromb Vasc Biol. 2009 Dec;29 (12) :2054-60.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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