ITX5061
ITX5061 is a type II inhibitor of p38 MAPK and also an antagonist of scavenger receptor B1 (SR-B1) .
Product Specifications
CAS Number
[1252679-52-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; HCV; p38 MAPK
Type
Reference compound
Related Pathways
Anti-infection; Autophagy; MAPK/ERK Pathway
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ITX5061.html
Purity
99.69
Solubility
DMSO : ≥ 83.3 mg/mL
Smiles
O=C(NC1=CC(C(C)(C)C)=CC(NS(=O)(C)=O)=C1OC)C(C2=C3C=CC=CC3=C(OCCN4CCOCC4)C=C2)=O.Cl
Molecular Formula
C30H38ClN3O7S
Molecular Weight
620.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Masson D, et al. Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. Arterioscler Thromb Vasc Biol. 2009 Dec;29 (12) :2054-60.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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