AIP (myristoylated)

Product Specifications

Product Name Alternative

Autocamtide-2-related inhibitory peptide (myristoylated)

Certification

RUO

Source

Synthetic.

Sequence

N-Myr-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu

Stability

As indicated on product label or CoA when stored as recommended.

Purity

≥95% (HPLC)

Solubility

Soluble in 30% Acetic Acid in Water (5 mg/ml) .

Molecular Weight

1708.1

Shipping Conditions

Blue Ice

Storage Conditions

-20°C

Notes

AIP (autocamtide-2-related inhibitory peptide, Prod. No. BML-P211) is a highly-specific and potent inhibitor of CaM kinase II. The sequence is derived from autocamtide-2 (Prod. No. BML-P101) but alanine is substituted for threonine at the 9-position. AIP at 1 μM completely inhibited CaM kinase II but did not affect PKC, PKA, CaMKIV and other brain extract kinases. Myristoylated AIP (Prod. No. BML-P212) is the same sequence as AIP but is N-terminal myristoylated to increase cell-permeability.