PPDA
PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D containing receptors[1].
Product Specifications
CAS Number
[684283-16-7]
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ppda.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H]([C@@H](NCC1)C(O)=O)C(O)=O)C2=CC3=CC=C(C=CC=C4)C4=C3C=C2
Molecular Formula
C21H18N2O5
Molecular Weight
378.38
References & Citations
[1]Kinarsky L, et al. Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamate-binding pocket. J Pharmacol Exp Ther. 2005 Jun;313 (3) :1066-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Curated Selection
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